For centuries, industrial hemp (plant species Cannabis sativa) has been a source of fiber and seed oil used worldwide to produce a variety of industrial and consumer products. Currently, more than 30 nations grow industrial hemp as an agricultural commodity, which is sold on the world market. In the United States, however, production is strictly controlled under existing laws.
Until further notice, North Carolina will continue to operate under the Industrial Hemp Pilot Program authorized in 2014.
Hemp production has been legalized in North Carolina, but only as part of the state’s pilot program as allowed under federal law. The N.C. General Assembly passed Senate Bill 313 in 2015, allowing the Industrial Hemp Commission to develop the rules and licensing structure necessary to stay within federal laws. The law was modified in 2016 in House Bill 992. The Industrial Hemp Commission adopted temporary rules for review in February 2017; these were approved by the Rules Review Commission of the Office of Administrative Hearings.
Medicinal Hemp and the Endocannabinoid system
Why Full Spectrum works better than Isolate:
“The Entourage Effect”
Whole-plant extracts typically contain a carefully measured amount of the cannabis plant’s most prominent cannabinoid, THC, although usually not in a large enough amount to have any psychological effects. When present together, CBD and its cannabinoid colleagues, as well as terpenes, produce what is known as an entourage effect. The synergistic relationship between cannabinoids and terpenes has been shown to increase the healing properties of each.
Full-spectrum cannabis extracts VS CBD isolate
A study published by the Lautenberg Center for Immunology and Cancer Research, which aimed its focus on the effectiveness of CBD isolate compared to full-plant extract, supported this concept, stating in its summary that “in all of the tests, the isolated CBD was ineffective both before and after a certain dosage, while the effectiveness of the full-spectrum solution continued to increase as higher doses were administered. The results all indicate that CBD is only effective against swelling and pain at a certain dose, and that cannabis solutions containing a full range of cannabinoids will continue to provide corresponding effects as the dosage is increased.”
Given the results of this study, it would seem to confirm that full-spectrum extract is preferable over CBD isolate for most CBD users, but CBD isolate is still frequently used and believed by some to be more effective than full-plant extract. This belief is led by the idea that CBD is the only medically sought after cannabinoid in the cannabis plant, aside from THC. Many CBD isolate users are under the impression that by consuming only the CBD cannabinoid and no terpenes or any other “unnecessary” components of the plant, they are getting a more powerful or effective dose of CBD. When vaping a CBD extract, which as stated previously, is considered to be the most efficient and quick-acting method of administering CBD, isolate users may feel that they are taking the most efficient route to CBD consumption. While this method might be efficient, the lack of entourage effect means the benefits are reduced when compared to full-spectrum CBD consumption.
Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?
A central tenet underlying the use of botanical remedies is that herbs contain many active ingredients. Primary active ingredients may be enhanced by secondary compounds, which act in beneficial synergy. Other herbal components may mitigate the side effects of dominant active ingredients. We reviewed the literature concerning medical cannabis and its primary active ingredient, 9-tetrahydrocannabinol (THC). Good evidence shows that secondary compounds in cannabis may enhance the beneficial effects of THC. Other cannabinoid and non-cannabinoid compounds in herbal cannabis or its extracts may reduce THC-induced anxiety, cholinergic deficits, and immunosuppression. Cannabis terpenoids and flavonoids may also increase cerebral blood flow, enhance cortical activity, kill respiratory pathogens, and provide anti-inflammatory activity.
What Makes “Whole Plant Medicine” Different?
“Whole plant medicine” is a term used to describe medicines utilizing the full spectrum of therapeutic compounds cannabis has to offer. A glimpse of the most abundant cannabinoids provided below:
As you can see, each of these therapeutic agents have so much to offer individuals with a wide breadth of symptoms and conditions.
Cannabis Plant Information
The Endocannabinoid System
Research on marijuana’s effects led directly to the discovery of a hitherto unknown biochemical communication system in the human body, the Endocannabinoid System, which plays a crucial role in regulating our physiology, mood, and everyday experience.
The discovery of receptors in the brain that respond pharmacologically to cannabis—and the subsequent identification of endogenous cannabinoid compounds in our own bodies that bind to these receptors—has significantly advanced our understanding of human biology, health, and disease.
It is an established scientific fact that cannabinoids and other components of cannabis can modulate many physiological systems in the human brain and body. Cannabinoids are chemical compounds that trigger cannabinoid (and other) receptors. More than 100 cannabinoids have been identified in the marijuana plant. Of these marijuana molecules, tetrahydrocannabinol (THC) and cannabidiol (CBD) have been studied most extensively. In addition to cannabinoids produced by the plant, there are endogenous cannabinoids (such as anandamide and 2AG) that occur naturally in the mammalian brain and body, as well as synthetic cannabinoids created by pharmaceutical researchers.
Finding the correct dose for each person is not an easy task, even for experts. There are so many different factors that play important roles and everyone’s experience is different.
Some of the factors may include:
- The medical condition or problem.
- The stage or intensity of condition
- The individuals biology
- The individuals Endocannabinoid system
- Body weight
- The individuals sensitivity to cannabis
- Body chemistry (food, pharmaceuticals, etc.
In 1995, researchers found that cannabinoids like CBD and THC could benefit the body and brain in numerous ways.
Later, they discovered that each cannabinoid has a unique relationship with the endocannabinoid system.
For example, THC induces psychoactive effects linked to “getting high”, but it’s also a strong analgesic and anti-inflammatory.
CBD, on the other hand, is not intoxicating. In other words, it won’t make you high. In fact, it can even alter the psychoactive effects of THC. It delivers a range of health benefits, such as relief from stress and anxiety or altered perception of pain.
At lower doses, CBD can be mildly stimulating, while higher amounts tend to bring sedative effects.
Other cannabinoids, such as cannabigerol (CBG) or cannabinol (CBN) have their own set of effects. The full collection of cannabinoids creates something known as the “cannabinoid spectrum.”
THC vs CBD information
We are happy to share our North Carolina state test results with our customers. Our private testing results are available upon request!
Winter 2018 Greenhouse crop (pdf)
Summer 2019 state testing (pdf)
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